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Guilhian Leipnitz Selected Research

3-methylglutaric acid

6/2022Antioxidant system disturbances and mitochondrial dysfunction induced by 3-methyglutaric acid in rat heart are prevented by bezafibrate.
4/2020In vivo evidence that bezafibrate prevents oxidative stress and mitochondrial dysfunction caused by 3-methylglutaric acid in rat liver.

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Guilhian Leipnitz Research Topics

Disease

9Glutaric Acidemia I
11/2019 - 01/2007
7Mitochondrial Diseases (Mitochondrial Disease)
06/2022 - 08/2014
6Ethylmalonic encephalopathy
04/2022 - 01/2012
62-Hydroxyglutaricaciduria
01/2018 - 01/2002
5Nonketotic Hyperglycinemia
01/2019 - 08/2011
4Brain Diseases (Brain Disorder)
08/2022 - 01/2017
4Ataxia (Dyssynergia)
06/2022 - 02/2013
4Body Weight (Weight, Body)
12/2019 - 06/2008
4Seizures (Absence Seizure)
11/2019 - 08/2012
4Short chain Acyl CoA dehydrogenase deficiency
08/2014 - 12/2002
3Phenylketonurias (Phenylketonuria)
06/2021 - 03/2010
3Atrophy
01/2021 - 03/2010
3Hypermethioninemia
04/2019 - 01/2018
3Infections
09/2018 - 12/2015
3Inborn Genetic Diseases (Disease, Hereditary)
06/2013 - 11/2009
3Refsum Disease (Refsum's Disease)
02/2013 - 08/2010
3Brain Injuries (Brain Injury)
01/2013 - 12/2005
3Glioma (Gliomas)
09/2010 - 01/2007
3Neurodegenerative Diseases (Neurodegenerative Disease)
06/2009 - 12/2005
2Inflammation (Inflammations)
12/2020 - 04/2017
2Epilepsy (Aura)
11/2019 - 10/2003
2Gliosis
10/2019 - 01/2018
2Cognitive Dysfunction
03/2019 - 10/2003
2Communicable Diseases (Infectious Diseases)
10/2017 - 06/2017
2Sulfite oxidase deficiency
01/2017 - 12/2013
2Metabolic Diseases (Metabolic Disease)
11/2013 - 12/2012
2Cerebellar Ataxia (Dysmetria)
08/2013 - 02/2013
2Peroxisomal Disorders (Peroxisomal Disorder)
02/2013 - 03/2011
2Intellectual Disability (Idiocy)
12/2012 - 03/2010
2Medium chain acyl CoA dehydrogenase deficiency
08/2012 - 11/2007
2Hyperlysinemias (Hyperlysinemia)
02/2011 - 06/2009
2isovaleric Acidemia
03/2009 - 08/2008
1Dilated Cardiomyopathy (Cardiomyopathy, Congestive)
06/2022
1Barth Syndrome
06/2022
1Heart Failure
06/2022
1Liver Diseases (Liver Disease)
10/2021
1Parasitic Diseases (Parasitic Disease)
12/2020
1Argininosuccinic Aciduria
02/2020

Drug/Important Bio-Agent (IBA)

14AcidsIBA
06/2022 - 01/2002
8Glutaryl-CoA DehydrogenaseIBA
08/2022 - 08/2015
7AntioxidantsIBA
06/2022 - 12/2005
7Biological ProductsIBA
10/2021 - 02/2011
7Lysine (L-Lysine)FDA Link
11/2019 - 06/2009
5Reactive Oxygen Species (Oxygen Radicals)IBA
11/2019 - 09/2010
5Glycine (Aminoacetic Acid)FDA LinkGeneric
01/2019 - 08/2011
5Adenosine Triphosphatases (ATPase)IBA
07/2018 - 06/2009
5HHH syndromeIBA
08/2015 - 11/2009
4BezafibrateIBA
06/2022 - 01/2017
4ethylmalonic acid (ethylmalonate)IBA
01/2021 - 05/2003
4EnzymesIBA
11/2019 - 06/2003
4Tryptophan (L-Tryptophan)FDA Link
11/2019 - 06/2008
4Creatine Kinase (Creatine Phosphokinase)IBA
10/2017 - 06/2003
3S-Adenosylmethionine (Ademetionine)IBA
10/2021 - 07/2018
3Phenylalanine (L-Phenylalanine)FDA Link
06/2021 - 03/2010
3Fatty Acids (Saturated Fatty Acids)IBA
01/2019 - 08/2012
3SulfitesIBA
01/2017 - 12/2013
3OrnithineIBA
08/2013 - 11/2009
3homocitrullineIBA
08/2013 - 11/2009
3Phytanic AcidIBA
02/2013 - 08/2010
3Glutathione (Reduced Glutathione)IBA
12/2012 - 12/2005
23-methylglutaric acidIBA
06/2022 - 04/2020
2Hydrogen Sulfide (Sulfide, Hydrogen)IBA
04/2022 - 01/2017
2Phenylalanine Hydroxylase (Phenylalanine 4 Monooxygenase)IBA
06/2021 - 12/2019
2HMGA ProteinsIBA
04/2020 - 05/2019
2HydroxylysineIBA
11/2019 - 01/2019
2CatalaseIBA
11/2019 - 12/2012
2Brain-Derived Neurotrophic Factor (BDNF)IBA
03/2019 - 01/2018
2Amino AcidsFDA Link
01/2019 - 02/2011
2Proteins (Proteins, Gene)FDA Link
01/2019 - 01/2018
2SilverIBA
09/2018 - 10/2017
2Electron Transport Complex IV (Cytochrome c Oxidase)IBA
01/2018 - 01/2002
2Sulfite OxidaseIBA
01/2017 - 11/2016
2ThiosulfatesIBA
11/2016 - 12/2013
2Quinolinic AcidIBA
11/2016 - 12/2005
2glutaric acidIBA
08/2015 - 01/2007
2AmmoniaIBA
08/2013 - 12/2012
2Thiobarbituric Acid Reactive SubstancesIBA
06/2010 - 12/2005
2isovaleric acidIBA
03/2009 - 08/2008
2KynurenineIBA
01/2007 - 12/2005
1dichloromaleic acid (DCMA)IBA
06/2022
1sulfur dioxygenaseIBA
04/2022
1Adenosine KinaseIBA
10/2021
1Glycine N-Methyltransferase (Glycine Sarcosine N-Methyltransferase)IBA
10/2021
1Mitochondrial DNA (mtDNA)IBA
10/2021
1AdenosylhomocysteinaseIBA
10/2021
1OrganophosphatesIBA
12/2020
1Trichlorfon (Metrifonate)IBA
12/2020
1InsecticidesIBA
12/2020
1LipopolysaccharidesIBA
12/2020
1Free Radical ScavengersIBA
02/2020
1Argininosuccinic AcidIBA
02/2020
1Valproic Acid (Depakote)FDA LinkGeneric
11/2019
1Superoxide DismutaseIBA
11/2019
14-Aminopyridine (4 Aminopyridine)FDA Link
11/2019
1Anticonvulsants (Antiepileptic Drugs)IBA
11/2019
1Neuroprotective AgentsIBA
11/2019
1PicrotoxinIBA
11/2019
1Diazepam (Valium)FDA LinkGeneric
11/2019

Therapy/Procedure

3Therapeutics
02/2020 - 06/2015
3Subcutaneous Injections
01/2018 - 06/2008